Theory and Practice in Medicine, 2016, 22 tomas No. 5
SECONDARY CAUSES OF DYSLIPIDEMIA
Sandra Kutkienė, Žaneta Petrulionienė, Rolandas Sausdravas, Ieva Šarapnickienė, Marija Petrylaitė, Irma Rutkauskienė, Urtė Gargalskaitė, Milda Kovaitė,E gidija Rinkūnienė, Vilma Dženkevičiūtė, Vytautas Kasiulevičius
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Key words: Secondary lipid disorders, diagnostics, treatment.
Secondary lipid disorders are the most common cause of abnormal lipid profiles in the general population. It is very important to exclude secondary causes, such as diet, other diseases, medications, that could cause dyslipidemia. If a patient suddenly develops a lipid abnormality or the lipid profile suddenly worsens, the secondary cause should be considered. Patients with
familial hypercholesterolemia can have their disorder worsen if they develop secondary causes that adversely affect lipid levels. However, if the secondary cause is treated, the lipid abnormality can greatly improve or even disappear. One of the diseases that could affect lipid profile is hypothyroidism, therefore it is highly recommended to check thyroid-stimulating hormone
level. Other disorders that cause elevations in low density lipoprotein cholesterol levels should be obvious on routine history,physical examination, and laboratory screening. If a patient has elevated triglyceride levels the diet history and medication list should be taken. It is extremely important to perceive that many common disease states can adversely impact triglyceride
levels including obesity, poorly controlled diabetes, chronic renal failure, human immunodeficiency virus, and inflammatory disorders. In patients with a low high density lipoprotein cholesterol level the medications list and diet should be assessed. In order to determine secondary lipid disorders it is necessary to examine patient consistently, collect medical history, to evaluate the state of a patient by an objective assessment. The specific treatment can be taken into consideration only after a comprehensive examination of the patient and elimination of the causes of secondary dyslipidemia.
November 30, 2016 Accepted:
December 19, 2016