Theory and Practice in Medicine, 2016, 22 tomas No. 5
HYPOCALCAEMIA ‒ KNOWN BUT UNRECOGNIZED CONDITION. A CASE REPORT AND A SHORT REVIEW OF LITERATURE
Airida Narkutė, Gytė Damulevičienė
Correspondence Address: firstname.lastname@example.org
Key words: hypocalcaemia, primary hypoparathyroidism, long QT interval, parkinsonism.
Hypocalcaemia affects nervous and muscular systems, the main clinical symptoms include tetany, seizures, laryngospasm and arrythmias, the condition worsens heart failure. Primary hypoparathyroidism is a rare endocrine disorder that causes hypocalcaemia, significantly elevated plasma phosphorus and low parathormone concentration. Hypocalcaemia can also be
caused by pseudohypoparathyroidism, when serum concentration of parathormone is normal or elevated, vitamin D deficiency, acute or chronic renal failure, acute pancreatitis, various medication. We present a clinical case of clinically relevant hypocalcaemia due to primary hypoparathyroidism. Clinical presentation included seizures, epileptiformic activity on EEG,
long QT interval on ECG, and calcification of basal ganglia and cerebellum that potentially has caused parkinsonism. We started treatment with calcium gluconate intravenously wich was folowed by calcium and alphacalcidol. Patient’s condition improved, seizures did not repeat, however it was difficult to maintain normal blood calcium concentration, long QT interval
persisted on ECG. The patient was consulted by endocrinologist and diagnosed with primary hypoparathyroidism. For the following treatment it was recommended to continue taking calcium and alphacalcidol, and to monitor blood calcium and phosphorus concentrations.
June 13, Accepted:
November 28, 2016